The Effect of Gabapentin (Neurentin) and Pregabalin (Lyrica) in Pain Reduction After Photorefractive Keratectomy (PRK)

Shahid Beheshti University of Medical Sciences

Status and phase: Unknown; Phase 1

Conditions: Refractive Errors

Treatments: Drug: Pregabalin

Study type: Interventional

Funder types: Other

Identifiers

NCT01122004

8877

Details and patient eligibility

About

The studied patients will be given randomly one of three following drugs1:Gabapentin2: Pregabalin or placebo for 3 days after Photorefractive keratectomy surgery. The pain will be measured based on visual analog scale(VAS) on the day of operation and on the 3 rd day (morning, evening) and then compared among three groups.

Sex: All

Ages: 17+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients candidate for PRK, 17<age<70

Exclusion criteria

• use of any systemic analgesic drugs, drug intolerance, need of systemic or topical administration of NSAIDs or eye drops for allergy and glaucoma, dry eyes, pregnancy, breast feeding

Trial design

0 participants in 2 patient groups

Gabapentin

Active Comparator group

Treatment:

Drug: Pregabalin

Drug: Pregabalin

Pregabalin

Active Comparator group

Treatment:

Drug: Pregabalin

Drug: Pregabalin