The Effect of Gastric Bypass Surgery on Gut Hormones Related to Bone Remodeling and Intestinal Growth.

University of Copenhagen

Status: Completed

Conditions: Obesity; Bone Loss

Treatments: Other: Meal test and dexa scan

Study type: Observational

Funder types: Other

Identifiers

NCT01700686

GBPK

Details and patient eligibility

About

The overall purpose is to explore the link between the gut and the bones by investigating meal stimulated changes in the blood level of a number of hormones and markers related to intestinal growth and bone turnover in patients undergoing surgery for obesity (gastric bypass). The hormones will be measured in blood samples taken before and after surgery. The results are compared with changes in body weight and body composition as measured by DEXA scanning.

Enrollment: 18 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Caucasians fulfilling the criteria for laparoscopic gastric bypass.
• BMI>40kg/m2.

Exclusion criteria

• Pregnancy
• Chronic obstructive pulmonary disease
• Diabetes mellitus
• Chronic inflammatory bowel disease
• Major psychiatric disorder
• Drug abuse

Trial design

18 participants in 1 patient group

Obese subjects

Description:

Meal test and dexa scan

Treatment:

Other: Meal test and dexa scan