The Effect of General and Spinal Anesthesia on Neutrophil-to-lymphocyte Ratio

Antalya Training and Research Hospital

Status

Completed

Conditions

Anesthesia, Spinal

Anesthesia, General

Umbilical Cord

Treatments

Other: General anesthesia

Other: Spinal anesthesia

Study type

Observational

Funder types

Other

Identifiers

NCT05409885

5/4

Details and patient eligibility

About

The aim of the study was to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV) in patients undergoing cesarean section.

Full description

This study was designed to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord NLR, PLR and MPV in patients undergoing cesarean section.

The primary endpoint was to compare the effects of general and spinal anesthesia on umbilical cord NLR. Secondary endpoints were determined the general and spinal anesthesia on routine umbilical cord PLR, MPV and newborn Apgar scores at 1st and 5th min.

Enrollment

60 patients

Sex

All

Ages

18 to 45 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

18 - 45 years
American Society of Anesthesiology (ASA) II-III
elective ceserean surgery

Exclusion criteria

declining to give written informed consent
under 18 years of age or over 45 years of age
factors affecting NLR, PLR and MPV such as preeclampsia, HELLP syndrome or premature rupture of membranes
history of neurological and/or neuromucular disease
cooperation cannot be established
emergency surgery