The Effect of Group Treatment for Depression: A Study of Metacognitive Therapy, Mindfulness and Support Groups

University of Southern Denmark (SDU)

Status: Unknown

Conditions: Depression

Treatments: Behavioral: Metacognitive therapy; Behavioral: Support groups; Behavioral: Mindfulness based cognitive therapy, group

Study type: Interventional

Funder types: Other

Identifiers

NCT02538835

46332

Details and patient eligibility

About

This study evaluates the effect of metacognitive group therapy on depression compared to mindfulness groups and supportive groups. The participants, all with a history of depression and with current symptoms of depression, will be randomized to one of the three group interventions.

Full description

Metacognitive therapy (MCT) show promising results in alleviating depressive symptoms and reducing relapse of depression. However studies of MCT as a group intervention is limited and higher quality studies of the effectiveness of MCT is warranted. The present study aim to produce more conclusive evidence on the effect of MCT comparing MCT in groups with both and active control group and mindfulness based cognitive therapy (MBCT), which together with pharmacotherapy is currently one of the preferred treatment choices. Currently pharmacotherapy, cognitive therapy and MBCT seem to help 40-58% of the patients efficiently. The current studies of MCT indicate that this intervention may help a higher proportion of the patients.

Enrollment: 165 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consent to participate
• History of clinical depression
• Current depressive symptoms
• Verbal and cognitive abilities to complete the questionnaires during the study
• Stable medication - if any medication is ordinated
• Speaks fluently danish

Exclusion criteria

• If criteria for psychosis, bipolar disorder or personality disorder is matched
• known brain damage or mental retardation
• substance abuse
• women who are pregnant or breast feeding

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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165 participants in 3 patient groups, including a placebo group

Metacognitive Therapy

Experimental group

Treatment:

Behavioral: Metacognitive therapy

Mindfulness based cognitive therapy

Active Comparator group

Treatment:

Behavioral: Mindfulness based cognitive therapy, group

Support groups

Placebo Comparator group

Treatment:

Behavioral: Support groups