The Effect of Ingesting or Rinsing Sucrose and Sucralose on Self-control, Cognitive Performance, and Blood Glucose

University of Leeds

Status: Completed

Conditions: Self-control; Blood Glucose Response; Cognitive Performance

Treatments: Dietary Supplement: Ingestion of solution; Dietary Supplement: Rinising of solution

Study type: Interventional

Funder types: Other

Identifiers

NCT02075333

SN - 0114

Details and patient eligibility

About

The purpose of this study is to examine the effects of ingesting or mouth rinsing a sucrose (carbohydrate) versus a sucralose (carbohydrate-free) drink on self control, cognitive performance, and blood glucose level.

Enrollment: 40 patients

Sex: All

Ages: 50 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI 18 - 29 kg/m2

Exclusion criteria

• Dementia
• Depression
• Type 2 diabetes
• Phenylketonuria
• Intake of medication known to affect glucose metabolism
• Fasting blood glucose > 7.8 mmol/L

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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40 participants in 2 patient groups, including a placebo group

Sucrose (50g)

Active Comparator group

Description:

A 381g blackcurrant drink (cordial and water) providing 50g of sucrose

Treatment:

Dietary Supplement: Rinising of solution

Dietary Supplement: Ingestion of solution

Sucralose (0.92 g sugars)

Placebo Comparator group

Description:

A 381g blackcurrant drink (cordial and water) providing 0.92g of natural sugars

Treatment:

Dietary Supplement: Rinising of solution

Dietary Supplement: Ingestion of solution