The Effect of Injection Rate of Local Anesthetic in Caesarean Section

Karadeniz Technical University

Status: Completed

Conditions: Anesthesia, Spinal; Anesthesia, Obstetrical

Treatments: Other: Local anesthetic injection rate in spinal anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT05091294

Ahmet Beşir (Other Identifier)

2020-52

Details and patient eligibility

About

This randomized double-blind study aimed to compare the effects of two different subaracnoid lokal anesthetic injection rate in cesarean section. Totally 67 patients were included. The groups were compared in terms of maximum sensory and motor block level, time to reach T6 level, hemodynamic changes and nausea- vomiting saved.

Full description

A total of 67 patients 18-40 years undergoing cesarean, who were graded as American Society of Anesthesiologists physical status were randomly allocated into two groups, 120-sn injection time (n=34, Group F), 15-sn injection time (n=33, Group S). When the level of the sensory block achieve the T6 level the surgery was let to begin. The groups were compared in terms of hemodynamic values, use of efedrin, the time to achieve sensory block to the T6 level, maximum sensory block level and motor block level.

Enrollment: 67 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Anesthesiologists risk score (ASA) I-II risk status
• Singleton pregnancy aged
• Between 18-40 years

Exclusion criteria

• Pregnant women with contraindications for spinal anesthesia;
• Placental anomaly;
• Hypertension
• Cardiac disease
• Vascular disease
• Hepatic disease
• Renal disease
• Hemodynamic instability
• Spinal deformity;
• Severe mental retardation
• Weight < 50 kg or >110 kg; height < 140 cm or > 180 cm
• Metabolic and Acid-base balance disorders
• Emergency patients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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67 participants in 2 patient groups

Group S:33

Active Comparator group

Description:

120-second local anesthesic (% 0,5 Bupivacaine) injection time

Treatment:

Other: Local anesthetic injection rate in spinal anesthesia

Group F:34

Active Comparator group

Description:

15-second local anesthesic(% 0,5 Bupivacaine) injection time

Treatment:

Other: Local anesthetic injection rate in spinal anesthesia