The Effect of Inspiratory Muscle Training With Substance Use Disorder

Uskudar University

Status: Begins enrollment this month

Conditions: Pulmonary Function; Rehabilitation; Substance Abuse Disorder; Exercise

Treatments: Other: control group; Other: Inspiratory muscle training programme

Study type: Interventional

Funder types: Other

Identifiers

NCT06961838

ÜsküdarÜ2025

Details and patient eligibility

About

The aim was to investigate the effectiveness of inspiratory muscle training on dyspnoea, pulmonary function, respiratory muscle strength, cough capacity, functional exercise capacity, substance craving, depression, anxiety and quality of life in individuals with substance use disorder.

Full description

In recent years, substance use has increased among young people in our country, and studies investigating the negative effects of substances on pulmonary health have also increased. It has been emphasized in the literature that the most appropriate features should be determined for the exercise program in the treatment of individuals with SUD. Although studies in the literature have reported that substance use affects respiratory functions and creates a restrictive or obstructive pattern, no study investigating the effects of inspiratory muscle training has been found in the literature. To our knowledge, this study is the first to examine the effects of inspiratory muscle training on respiratory function in individuals with SUD. In our study, it was assumed that inspiratory muscle training could be a simple and inexpensive technique to improve dyspnea, respiratory functions, respiratory muscle strength, cough capacity, and exercise capacity in individuals with SUD, reduce substance cravings, increase quality of life, and reduce depression and anxiety, thus making it suitable for routine clinical use. The aim was to examine the effectiveness of inspiratory muscle training on dyspnea, respiratory functions, respiratory muscle strength, functional exercise capacity, substance craving, anxiety, depression, and quality of life in individuals with substance use disorders.

Enrollment: 34 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Being older than 18 years

  • Meeting the current Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) criteria for Substance Use Disorder
  • Receiving inpatient treatment
  • Substance use for more than one year
  • Being able to follow simple instructions
  • Not having any visual and auditory pathology
  • Being able to cooperate with the devices used.

Exclusion criteria

• Failure to comply with the treatment and assessment program
• Participation in a structured physiotherapy/exercise program in the last 6 months
• Presence of current psychotic symptoms
• Presence of any physical disability or medical problem
• Presence of respiratory system problems such as asthma and tuberculosis and infectious health problems (e.g. HIV, hepatitis B).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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34 participants in 2 patient groups

Inspiratory muscle training group

Experimental group

Description:

In addition to their standard treatment, individuals in the inspiratory muscle training group will participate in inspiratory muscle training for a total of 30 minutes with a threshold loading device (POWERbreathe®) for 15 minutes twice a day, 5 days a week for 4 weeks under the supervision of a physiotherapist.

Treatment:

Other: Inspiratory muscle training programme

Control group

Active Comparator group

Description:

Individuals in the control group will continue their standard treatment.

Treatment:

Other: control group