The Effect of Intraoperative Intravenous Lidocaine Infusion on Postoperative Pain and Recovery in Children (< 7 Years Old) Undergoing Thoracoscopic Surgery

Seoul National University

Status and phase

Enrolling

Phase 4

Conditions

Pain Management After Surgery

Treatments

Drug: Lidocaine (drug)

Drug: Saline infusion (placebo)

Study type

Interventional

Funder types

Other

Identifiers

NCT06710405

H2409-100-1573

Details and patient eligibility

About

This study aims to investigate the efficacy of intraoperative intravenous lidocaine infusion on postoperative pain management and recovery in pediatric patients undergoing thoracoscopic pulmonary resection.

Enrollment

80 estimated patients

Sex

All

Ages

6 months to 7 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Pediatric patients aged under 7 years undergoing thoracoscopic pulmonary resection

Exclusion criteria

cardiac dysfunction requiring vasopressors or inotropic agents
atrioventricular block or bradycardia
Liver or kidney dysfunction
Hypersensitivity to local anesthetics

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

80 participants in 2 patient groups, including a placebo group

Lidocaine group

Experimental group

Description:

Anesthesia induction is performed according to the standard protocol. Monitoring includes electrocardiography, pulse oximetry, arterial blood pressure, depth of anesthesia (Patient State Index, PSI), and pain score (Analgesia Nociception Index). In the lidocaine group, a single bolus dose of lidocaine 1.5 mg/kg is administered concurrently with the induction of anesthesia, followed by a continuous infusion of lidocaine at a rate of 1.5 mg/kg/hr.

Treatment:

Drug: Lidocaine (drug)

Control group

Placebo Comparator group

Description:

The control group receives a continuous infusion of normal saline in the same volume as that administered to the lidocaine group.

Treatment:

Drug: Saline infusion (placebo)