The Effect of Intraoperative Magnesium Sulfate Infusion on the Postoperative Recovery

Seoul National University

Status: Terminated

Conditions: Postoperative Pain

Treatments: Drug: Magnesium Sulfate; Drug: Normal saline

Study type: Interventional

Funder types: Other

Identifiers

NCT03206008

B-1608-360-006

Details and patient eligibility

About

Evaluating analgesic effect of intraoperative magnesium sulfate infusion in the outpatient surgery case

Enrollment: 11 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• aged between 18-65 year-old-patient (ASA I-II) who are planned to undergoing day surgery

Exclusion criteria

• ASA class ≥ III
• suspected imbalance of electrolyte
• myocardial damage or conduction delay
• myasthenia gravis or other neuromuscular disease
• impaired renal function
• already using any type of analgesia
• denial of participating in the study or not giving the informed consent

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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11 participants in 2 patient groups, including a placebo group

Normal saline group

Placebo Comparator group

Description:

after loading normal saline 100cc in 10-20 minutes, continuous infusion of normal saline until the end of surgery

Treatment:

Drug: Normal saline

Magnesium group

Active Comparator group

Description:

after loading magnesium sulfate dosing 50 mg/kg (100cc) in 10-20 minutes, continuous infusion of magnesium sulfate 15 mg/kg/h until the end of surgery

Treatment:

Drug: Magnesium Sulfate