The Effect of Intraoperative Ventilation Mode on Hemodynamics and Lung Dynamics

Izmir Ataturk Training and Research Hospital

Status: Enrolling

Conditions: Mechanical Ventilation

Treatments: Device: The mechanical ventilation mode

Study type: Observational

Funder types: Other

Identifiers

NCT05776589

Izmir ATRH

Details and patient eligibility

About

In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics and hemodynamics in patients undergoing vertebral surgery in the prone position.

Full description

The VCV (volume controlled ventilation) mode is the mode commonly used in general anesthesia practice. In VCV mode, the parameters under control are tidal volume and respiratory rate. In VCV mode, airway pressure changes depending on resistance and compliance. There is a risk of increased airway pressures in this mode.

In PCV-VG (pressure controlled volume guaranteed ventilation) mode, the parameters under control are the peak airway inspiratory pressure and the I/E ratio. It has been shown that peak airway pressures decrease and partial oxygen pressure increase due to decreased inspiratory flow in this ventilation mode.

Both ventilation modes are frequently used in patients undergoing general anesthesia.

In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics (pulmonary peak-plateau pressure, compliance, driving pressure, SpO2 and end-tidal carbon dioxide) and hemodynamics (mean arterial pressure and heart rate) in patients undergoing vertebral surgery in the prone position.

In the study, patients will be randomized and divided into 2 groups after obtaining informed consent forms. If a mode change is required during the surgery, that patient will be excluded from the study.

Enrollment: 72 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients who will undergo thoracolumbar vertebral surgery in the prone position
• Patients older than 18 years
• Patients younger than 70 years of age
• ASA 1-2 patients

Exclusion criteria

• Patients with a BMI >30 kg/m2
• Patients with a history of chronic pulmonary disease
• Patients with a history of previous thoracic surgery
• Patients with ASA >3
• Patients who will undergo emergency surgery
• Pregnant patients

Trial design

72 participants in 2 patient groups

Group PCV-VG

Description:

In this group, pressure-controlled volume guaranteed ventilation (PCV- VG) was applied in patients undergoing vertebral surgery in the prone position.

Treatment:

Device: The mechanical ventilation mode

Group VCV

Description:

In this group, volume-controlled ventilation (VCV) was applied in patients undergoing vertebral surgery in the prone position.

Treatment:

Device: The mechanical ventilation mode