The Effect of Intravenous Lidocaine on Pain After Tonsillectomy

Chung-Ang University Hosptial, Chung-Ang University College of Medicine

Status and phase: Unknown; Phase 4

Conditions: Postoperative Pain

Treatments: Drug: Intravenous normal saline injection; Drug: Intravenous lidocaine injection

Study type: Interventional

Funder types: Other

Identifiers

NCT01291979

ChungAngUH1

Details and patient eligibility

About

This prospective randomized study aims to evaluate the effectiveness of intravenous lidocaine injection on the relief of pain in patients undergoing tonsillectomy.

A total of 62 patients will be randomized into one of two groups (group C or group I) based on Excel number generation.

Patients in group C will receive received normal saline intravenous injection, and patients in group I will receive an intravenous bolus injection of 1.5 mg/kg lidocaine followed by a continuous lidocaine infusion of 2 mg/kg/hr.

Visual analogue scale pain scores, fentanyl consumption and the frequency at which patients pushed the button (FPB) of a patient-controlled analgesia system will be recorded at 4, 12, 24, 48 hours postoperatively.

Enrollment: 62 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Tonsillectomy

Exclusion criteria

• mental change
• allergy to local anesthetics

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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62 participants in 2 patient groups, including a placebo group

Intravenous lidocaine injection group

Active Comparator group

Description:

Patients in Group I (intravenous lidocaine injection group) received an intravenous bolus injection of 1.5 mg/kg lidocaine followed by a continuous lidocaine infusion of 2 mg/kg/hr.

Treatment:

Drug: Intravenous lidocaine injection

Placebo control group

Placebo Comparator group

Description:

Patients in Group C (placebo control group) received normal saline intravenous injection

Treatment:

Drug: Intravenous normal saline injection