The Effect of Intravenous Magnesium Sulfate on Intraocular Pressure Following Tracheal Intubation

Shiraz University of Medical Sciences

Status and phase: Completed; Phase 3

Conditions: Increased Intra Ocular Pressure (IOP)

Treatments: Drug: Magnesium Sulfate; Drug: normal saline

Study type: Interventional

Funder types: Other

Identifiers

NCT01241175

4286

Details and patient eligibility

About

The aim of this study is to assess the effect of preoperatively administered intra venous magnesium sulfate in attenuating pressure response to laryngoscopy and endotracheal intubation in adult patients scheduled for elective non ocular surgery

Sex: All

Ages: 18 to 38 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 to 38 years old
• ASA I
• scheduled for elective ENT ambulatory surgeries under general anesthesia

Exclusion criteria

• specific major hepatic, renal and cardio-vascular disease
• known to have allergic reaction to magnesium sulphate or other drugs , -hypermagnesemia
• hypocalcemia
• anuria
• heart block
• pregnancy
• any degree of renal insufficiency
• digitalised patients
• positive history of glaucoma or intra ocular hypertension
• refused to participate

Trial design

0 participants in 2 patient groups, including a placebo group

magnesium sulfate

Experimental group

Treatment:

Drug: Magnesium Sulfate

normal saline

Placebo Comparator group

Treatment:

Drug: normal saline