The Effect of Lateral Tilt on Ventilation Distribution in Lungs Assessed by Electrical Impedance Tomography (N-LAT-EIT)

Regional Hospital Liberec

Status: Completed

Conditions: Lung Collapse

Treatments: Other: Body positioning; Device: Bed tilting

Study type: Interventional

Funder types: Other

Identifiers

NCT04235231

RHL-NICU-2020-01

Details and patient eligibility

About

Prevention of lung inhomogeneity is an essential part of preventive strategy in neurocritical care, reducing the risks of secondary brain damage from hypoxemia, hypo/hypercapnia or pneumonia.

Full description

In the monocentric, intervention, prospective, randomized study, the investigators will examine the effect of lateral tilting (routinely used in critical care) on the lung inhomogeneity that will be analyzed by electrical impedance tomography (EIT) in the unconscious patients with acute primary brain disease and artificial pulmonary ventilation. Two types of lateral tilting will be compared: manual positioning of body by nurse versus the bed tilting (15° lateral tilt, original company (LINET) and product brand name (Eleganza 5).

Enrollment: 250 patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Primary brain disease
• Hospitalization in Neurocenter, Neurointensive Care Unit
• Age>18 years
• Unconsciousness
• Artificial pulmonary ventilation

Exclusion criteria

• Intracranial hypertension
• History of primary lung disease
• The terminal stage of the disease
• Refractory hemodynamic instability

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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250 participants in 2 patient groups

Lateral tilt bed

Experimental group

Description:

Bed tilting (15° lateral tilt, original product brand name LINET Eleganza 5)

Treatment:

Device: Bed tilting

Body positioning

Experimental group

Description:

Manual positioning of body by nurse.

Treatment:

Other: Body positioning