The Effect of Leucine on Body Composition and Muscle Characteristics in Elderly, Type 2 Diabetes Patients

Maastricht University Medical Centre (MUMC)

Status and phase: Completed; Phase 3; Phase 2

Conditions: Type 2 Diabetes

Treatments: Dietary Supplement: Wheat flour; Dietary Supplement: Leucine

Study type: Interventional

Funder types: Other

Identifiers

NCT00643773

MEC-07-1111

Details and patient eligibility

About

The purpose of this study is to determine whether long term leucine supplementation has a positive effect on body composition and muscle characteristics in elderly, type 2 diabetes patients.

Enrollment: 60 estimated patients

Sex: Male

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of type 2 diabetes

Exclusion criteria

• Impaired renal or liver function
• Cardiac disease
• Subjects with metal implants
• Hypertension
• Diabetes complications
• Exogenous insulin therapy

Trial design

60 participants in 2 patient groups, including a placebo group

A

Experimental group

Description:

Leucine supplement

Treatment:

Dietary Supplement: Leucine

B

Placebo Comparator group

Description:

Wheat flour

Treatment:

Dietary Supplement: Wheat flour