The Effect of Lidocaine Patch for Postoperative Pain

BON WOOK KOO

Status and phase: Completed; Phase 4

Conditions: Acute Pain

Treatments: Drug: Group L

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT04754451

LDPS

Details and patient eligibility

About

The lidocaine patch is currently only permitted for post herpetic neuralgia but the investigators want to study its effectiveness in post operative pain after inguinal herniorrhaphy

Full description

After open unilateral inguinal herniorrhaphy, patients are randomly divided into group L and group P groups. Group L attaches two lidocaine patches for 12 hours, above and below the incision site. Group P attaches two placebo patches for 12 hours, above and below the incision site. Pain scores are recorded for 30 minutes, 2 hours, 24 hours, and 1 week after surgery.

Enrollment: 32 patients

Sex: All

Ages: 19 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists physical status I - II
• Scheduled open unilateral herniorrhaphy

Exclusion criteria

• body mass index (BMI) < 18.5 or ≥ 35 kg/m2
• severe renal or hepatic dysfunction
• allergy to amide-based local anesthetic agents
• taking class 1 antiarrhythmic drugs (tocainide and mexiletine, etc.)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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32 participants in 2 patient groups

Group P(placebo)

No Intervention group

Description:

Attach two placebo patches for 12 hours, above and below the incision site.

Group L(lidocaine patch)

Experimental group

Description:

Attach two lidocaine patches for 12 hours, above and below the incision site.

Treatment:

Drug: Group L