The Effect of Liquorice on Plasma Potassium

University of Oulu

Status: Terminated

Conditions: Healthy

Treatments: Other: Liquorice 102 g/day; Other: Liquorice 66 g/day

Study type: Interventional

Funder types: Other

Identifiers

NCT00927017

Lakritsi-2

Details and patient eligibility

About

The hypothesis is that liquorice lowers plasma potassium. This study aims to elucidate the dose-response of this effect with two doses of liquorice (66 grams or 102 grams) per day for two weeks.

Enrollment: 9 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy volunteers
• age 18-40

Exclusion criteria

• any continuous medication
• hypertension or hypotension
• allergy to liquorice
• pregnancy or lactation
• difficult venipuncture
• drug or alcohol abuse
• participation in pharmaceutical trial

Trial design

9 participants in 2 patient groups

Liquorice 66 g/day

Active Comparator group

Description:

Liquorice given 66 grams per day for two weeks

Treatment:

Other: Liquorice 66 g/day

Liquorice 102 g/day

Active Comparator group

Description:

Liquorice given 102 grams per day for two weeks

Treatment:

Other: Liquorice 102 g/day