The Effect of Local Injectet GH on the Collagen Synthesis in the Ligamentum Patella

University of Aarhus

Status: Completed

Conditions: Growth Hormone; Elderly

Treatments: Drug: Growth Hormone

Study type: Interventional

Funder types: Other

Identifiers

NCT01158612

H-2-2010-039

Details and patient eligibility

About

Tendon and ligament injuries are a frequent problem among athletes but also in the general population. The healing process is a prolonged process, and complete recovery of tissue strength is nearly never reached. The purpose of this study is to examine the effect of local injection of human Growth Hormone on tendon collagen synthesis.

Full description

Tendon and ligament injuries are a frequent problem among athletes but also in the general population. The healing process is a prolonged process, and complete recovery of tissue strength is nearly never reached. The purpose of this study is to examine the effect of local injection of human Growth Hormone on tendon collagen synthesis.

in order to investigate the collagen synthesis potential and the influence of growth hormone, 12 elderly males age > 50 year, is enrolled in this study.

Enrollment: 12 patients

Sex: Male

Ages: 55 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI 18.5 - 25.0

Exclusion criteria

• earlier knee injury

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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12 participants in 2 patient groups, including a placebo group

Growth hormone

Experimental group

Description:

The effect of Growth hormone on the collagen synthesis rate

Treatment:

Drug: Growth Hormone

Saline

Placebo Comparator group

Treatment:

Drug: Growth Hormone