The Effect of Low Dose Ketamine on Narcotic Consumption in Patients Undergoing Laparoscopic Cholecystectomy

Aga Khan University

Status: Completed

Conditions: Cholelithiasis

Treatments: Drug: Ketamine Hydrochloride

Study type: Interventional

Funder types: Other

Identifiers

NCT05444777

2387-Ane-ERC-12

Details and patient eligibility

About

This double-blinded randomized control trial aims to analyze the effect of low dose Ketamine on narcotic consumption, in patients undergoing Laparoscopic cholecystectomy.

Enrollment: 86 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• all ASA 1 and 2 patients undergoing Laparoscopic Cholecystectomy electively.

Exclusion criteria

• Hepatic and renal disease and ASA 3 and 4 patients.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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86 participants in 2 patient groups

Ketamine group (Group K)

Experimental group

Description:

Group K was given ketamine @ 0.5mg/kg (prepared by dilution in 0.9% normal saline in 10 ml syringe) at the time of wound closure.

Treatment:

Drug: Ketamine Hydrochloride

Saline group (Group S)

Other group

Description:

Group S was given saline in 10 ml syringe

Treatment:

Drug: Ketamine Hydrochloride