The Effect of Luteinizing Hormone (LH) Supplementation Following Gonadotropin-releasing Hormone (GnRH) Antagonist Administration in Advanced Reproductive Ageing Women Undergoing IVF and Embryo Transfer (IVF/ET)

Baruch Padeh Medical Center

Status and phase: Completed; Phase 4

Conditions: Pregnancy Result Rape

Treatments: Drug: Leuveris

Study type: Interventional

Funder types: Other

Identifiers

NCT01016210

Leuveris1.CTIL

Details and patient eligibility

About

To explore whether recombinant LH (rLH) supplementation (Leuveris) to recombinant follicle stimulating hormone (rFSH) following GnRH antagonist treatment has an advantage in infertile women with advanced reproductive ageing undergoing IVF-ET.

Enrollment: 60 estimated patients

Sex: Female

Ages: 25 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• female candidate to IVF
• between 30-45 years old

Exclusion criteria

• not included for fertilization

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

60 infertile women

Experimental group

Description:

Candidates for IVF-ET treatment

Treatment:

Drug: Leuveris

Drug: Leuveris

control

No Intervention group

Description:

no treatment