The Effect of Meal Composition on Blood Lipids

Texas Christian University

Status

Completed

Conditions

Dyslipidemia

Treatments

Other: High-Protein Condition

Other: High-Monounsaturated Fat Condition

Study type

Interventional

Funder types

Other

Identifiers

NCT02529709

TexasCU

Details and patient eligibility

About

The purpose of this study is to see if a high-protein meal leads to a better postprandial (after a meal) blood lipid profile compared to a high-monounsaturated meal.

Full description

The effect of a high-protein diet compared to a high-monounsaturated fat diet on fasting lipids is controversial (1,2), In addition, these studies did not examine the effect of a high-protein compared to a high-monounsaturated meal on postprandial lipid concentrations. Postprandial lipid responses are important to examine since they are associated with heart disease (3,4). In addition, most individuals in Western countries are in a postprandial state for majority of the day. The present study will compare the effect of a high-protein meal versus a high-monounsaturated fat meal on postprandial lipid responses.

Enrollment

24 patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Men and women ages 18-65 years.

Exclusion criteria

Use of medications or supplements that affect lipid levels, body weight, or blood glucose,
following a weight loss diet,
being a vegan,
smoking,
heavy alcohol use,
pregnancy,
lactation,
severe depression,
eating disorders,
presence of liver, kidney, gastrointestinal, adrenal, or untreated thyroid disease,
diabetes,
lactose intolerance,
documented mal-absorption, or
bowel surgery that affects absorption.