The Effect of Meat and Food Drived Polyphenols on Oxidize LDL Level

Hadassah Medical Center

Status: Completed

Conditions: Healthy

Treatments: Other: meat meals; Other: frozen meat cutlets meal

Study type: Interventional

Funder types: Other

Identifiers

NCT01389492

MWPP09-HMO-CTIL

Details and patient eligibility

About

The postprandial increase in MDA level following meat meal could cause modification to LDL particles in healthy volunteers. Co-consumption of food drived polyphenols with the meat will result in a significant decrease in LDL modification.

Enrollment: 14 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy adults, normal BMI

Exclusion criteria

• Metabolic disorders
• Smokers
• Drinkers
• Taking nutritional supplement

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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14 participants in 4 patient groups

frozen meat

Other group

Description:

250 g of frozen meat meal for 4 days

Treatment:

Other: meat meals

Other: frozen meat cutlets meal

frozen meat and wine

Other group

Description:

250 g of frozen meat and red wine for 4 days

Treatment:

Other: meat meals

Other: frozen meat cutlets meal

fresh meat

Other group

Description:

250 g of fresh meat meal

Treatment:

Other: meat meals

Other: frozen meat cutlets meal

fresh meat and wine

Other group

Description:

250 g of fresh meat meal

Treatment:

Other: meat meals

Other: frozen meat cutlets meal