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The Effect of MediYoga on Sleep Quality, Blood Pressure, and Quality of Life in Older Adults with Hypertension:

H

Herlev and Gentofte Hospital

Status

Enrolling

Conditions

Hypertension
Quality of Life
Quality of Sleep
Mental Health

Treatments

Behavioral: Intervention Group II, Yoga 40 minutes x2 pr week
Behavioral: Intervention group I, Yoga 20 minutes x2 pr week
Other: Control Group, No intervention

Study type

Interventional

Funder types

Other

Identifiers

NCT06553820
H-24000021

Details and patient eligibility

About

The goal of this Randomized Controlled Trial is to test if an intervention consisting of Yoga can increase quality of sleep and health related quality of life and decrease BP. Secondary to explore and describe the implementation of a yoga intervention and the participants' experiences and perspectives on the intervention in a process evaluation.

The main question it aims to contribute knowledge about intervention of Yoga in a home environment for individuals with hypertension aged 65 years or older. Participants will (if they got selected into one of the two interventions groups), participate in Yoga exercises delivered by an app for 2 times a week for 10 weeks. Researchers will compare the intervention groups with the control group to see if Medi yoga has an effect in older people with hypertension.

Full description

Hypertension is a common disease, and it is estimated that by 2025 one third of the world's population will have hypertension. The prevalence is increasing with age, and among older persons above the age of 90, 71% of women and 65 % of men have hypertension. Hypertension is related to cardiovascular illness, such as myocardial infarction, stroke, and death.

Poor subjective sleep quality has a significant association with an elevated risk of hypertension. Sleep disturbances are a significant risk factor for the development of depression in older adults. A recent review concluded that non-pharmacological interventions have the potential to improve self-reported sleep quality among older adults. There appears to be increasing evidence to support the long-term effect of virtual mindfulness-based interventions and their impact on sleep quality.

Several recent reviews have concluded that breathing exercises can be used as an alternative non-pharmacological therapy to lower blood pressure, but highlighted also that establish knowledge on duration and intensity needed to ensure the optimal effect.

The intervention follows the guidelines from MediYoga-MOSI, an evidence-based method developed in Sweden based on the classical kundalini tradition with elements from traditional Korean medicine and Ayurveda It has been adjusted to the Nordic context and is today used across the Swedish healthcare system.

The participants in the intervention group will participate in a breathing exercise, light yoga exercise and mindfulness intervention, as a review highlighted the effectiveness of combining these three elements. These programs will be translated into Danish and delivered via an app.

The participants will be randomly assigned to one of three groups: a control group, receiving usual care, or in one of two different intervention-groups in which the intervention takes place 2 times pr week for 10 weeks in addition to usual care. In group I the participants receive a 20-minute intervention, in group II the participants receive a 40-minute intervention. Participants receiving the intervention will be invited to participate online in follow-up sessions (after 2 and 6 weeks), where questions can be asked and adherence to intervention can be promoted

If the home-based MediYoga intervention proves effective, yoga exercises could serve as a supplementary treatment for blood pressure. Regular practice of MediYoga may also enhance patients' sleep quality and overall quality of life.

Statistical analysis will be performed using the Statistical Package for Social Sciences Program for the quantitative data. Descriptive statistics and inferential statistics will be used for data analysis. Descriptive statistics include frequency, percentage, mean and standard deviation, and inferential statistics include the chi-square test. The test of normality will be performed using the Shapiro-Wilk test. A paired t-test will apply to test for the significant differences within the groups and an unpaired t-test will be used to test for significant differences between the control and intervention groups. From comparable studies we expect an attrition rate of 50% since adherence to the intervention seem to be a challenge in comparable interventions where the patient must be physical active (like trials testing rehabilitation programs or yoga). Drop-out rate will be registered in a flowchart and both per protocol and intent-to-treat analyses will be performed. The level of significance was set as p<0.05. The analysis will be performed by a blinded statistician.

Enrollment

180 estimated patients

Sex

All

Ages

65+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Older people ≥65 years
  • Diagnosed with hypertension.
  • Speaking and reading Danish.
  • Being able to consent.
  • No comorbidity that restricts them from participating in the intervention.
  • Being the owner or user of a smartphone or tablet.

Exclusion criteria

  • Starting an antihypertension medication during the intervention
  • Antihypertension medication is changed (more than 10% increase or reduction in an already used drug or a switch to another drug) during the intervention, which includes diuretics, ACE inhibitors, Calcium-blockers, or Angiotensin-2-blockers.
  • Participated in mindfulness or yoga exercise regularly at any point during the last two years.
  • Patients who have diagnosed sleep disorders for example sleep apnea or narcolepsy.
  • Taking sleep medication regularly.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

180 participants in 3 patient groups

Intervention group I, yoga 20 minutes x2 pr week
Experimental group
Treatment:
Behavioral: Intervention group I, Yoga 20 minutes x2 pr week
Intervention Group II, yoga 40 minutes pr week
Experimental group
Treatment:
Behavioral: Intervention Group II, Yoga 40 minutes x2 pr week
Control group, no intervention
Other group
Description:
standard of care
Treatment:
Other: Control Group, No intervention

Trial contacts and locations

1

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Central trial contact

Signe Risom, associated Prof.; Katrine Amdi, MSc

Data sourced from clinicaltrials.gov

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