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Effect of Mild Sedation and Analgesia on Radial Artery Cannulation in Novice Residents

A

Affiliated Hospital of Jiaxing University

Status

Completed

Conditions

Sedation and Analgesia

Treatments

Drug: mild sedation and analgesia
Drug: control

Study type

Interventional

Funder types

Other

Identifiers

NCT05863455
2023-KY-297

Details and patient eligibility

About

The aim of this study is to conduct a prospective, single-center randomized controlled study to investigate the effect of mild midazolam combined with sufentanil on radial artery cannulation in novice operators.

Full description

outcome: patients discomfort,visual analogue scale,First-attempt success rate,the success rate of radial artery cannulation within 10 minutes, Complication rate

Enrollment

108 patients

Sex

All

Ages

20+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients who required arterial cannulation for continuous blood pressure monitoring
  • Aged >20years
  • ASA physical status of 1-3
  • BMI 18-28kg/m2
  • All patients agreed to participate in this study at the time of recruitment and signed an informed consent form.

Exclusion criteria

  • a positive Allen's test
  • infection at the puncture site
  • coagulation disorders; arterial diseases (such as Raynaud's disease or thromboangiitis obliterans)
  • use of vasoactive drugs within 30 minutes before measurement during the study
  • patients with arterial abnormalities and bends; hemorrhagic shock
  • arterial atherosclerosis; radial artery puncture within the past 30 days
  • chronic use of opioid or benzodiazepine drugs
  • and known allergies or adverse reactions to benzodiazepines or opioids.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

108 participants in 2 patient groups

mild sedation and analgesia
Experimental group
Description:
Intravenous injection of 0.1ug/kg sufentanil and 0.03mg/kg midazolam for sedation and analgesia before radial artery cannulation.
Treatment:
Drug: mild sedation and analgesia
control
Active Comparator group
Description:
Intravenous injection of an equivalent volume of saline before radial artery cannulation.
Treatment:
Drug: control

Trial contacts and locations

1

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Central trial contact

Qinghe Zhou; Yazhi Xi

Data sourced from clinicaltrials.gov

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