The Effect of Mouthwash Containing Pomegranate Peel Extract and Chlorhexidine Mouthwash on Bleeding on Brushing

Cairo University (CU)

Status: Unknown

Conditions: Gingival Bleeding

Treatments: Drug: Chlorhexidine; Drug: Pomegranates peel extract

Study type: Interventional

Funder types: Other

Identifiers

NCT02939092

CairoE

Details and patient eligibility

About

To evaluate the clinical effectiveness of mouthwash containing pomegranate peel extract and chlorhexidine mouthwash on bleeding on brushing and counting of streptococcus mutans among a group of Egyptian children with permanent dentition.

Full description

To evaluate the clinical effectiveness of mouthwash containing pomegranate peel extract and chlorhexidine mouthwash on bleeding on brushing and counting of streptococcus mutans among a group of Egyptian children with permanent dentition.

PICO:

Population (P): Children with full permanent dentition. Intervention (I): Pomegranates peel extract. Comparator (C): Chlorhexidine.

Outcome(O):

Primary outcome: Bleeding on brushing, criteria:Asking patient, unit:Binary. Secondary outcome:Counting streptococcus mutans, criteria: Agar plate, unit: CFUs/mL

Enrollment: 60 estimated patients

Sex: All

Ages: 12 to 15 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• children aged 12-15 years old.
• Cooperative children.
• Both genders.
• Medically free.

Exclusion criteria

• Children undergoing orthodontic treatment.
• Children using any other oral hygiene aid other than routine teeth brushing.
• Children with known history of allergy to any mouth rinse or drug.
• Parents unable to give informed consent.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Pomegranate peel extract

Experimental group

Description:

Pomegranate is antimicrobial, anti inflammatory and antioxidant

Treatment:

Drug: Pomegranates peel extract

Chlorhexidine

Active Comparator group

Description:

Chlorhexidine mouthwash is antiplaque treatment and effective against gingivitis

Treatment:

Drug: Chlorhexidine