The Effect of Multimodal Treatment of Rectal Cancer on Circulating Tumor Cells: A Prospective, Observational Study

The Institute of Molecular and Translational Medicine, Czech Republic

Status: Enrolling

Conditions: Rectal Cancer Patients

Study type: Observational

Funder types: Other

Identifiers

NCT07112937

LF_2023_0118 (Other Identifier)

01/RVO-FNOs/2023

Details and patient eligibility

About

The prospective study will focus on patients undergoing multimodal treatment for rectal cancer. The main objective of the study will be to monitor changes in circulating tumor cells (CTCs) in the peripheral blood of patients during multimodal treatment. For each patient enrolled in the study, peripheral blood samples will be collected at specified time intervals to determine the presence and quantity of CTCs.

The CTCs levels will be compared among rectal cancer patients with neoadjuvant chemoradiotherapy and without neoadjuvant chemotherapy.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: rectal cancer -

Exclusion Criteria: no other cancer

Trial design

150 participants in 2 patient groups

Rectal cancer patients with neoadjuvant chemoradiotherapy

Rectal cancer patients without neoadjuvant chemoradiotherapy