The Effect of Neuropathic Pain in Patients With Combat-related Extremity Injury

Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Status: Completed

Conditions: Neuropathic Pain

Treatments: Other: The effect of neuropathic pain on quality of life, depression and sleep quality

Study type: Observational

Funder types: Other

Identifiers

NCT04674631

8

Details and patient eligibility

About

It has been suggested that veterans with chronic pain might be at increased risk for the development of depression, anxiety and post-traumatic stress disorder. To date, most of the published studies have focused on chronic pain as a whole, and there are limited studies examining association of neuropathic pain with psychological comorbidity and quality of life.Combat related extremity injury significantly influences the patients' quality of life and psychological state. In this context, the purpose of this study is to illustrate to what extent neuropathic pain influences the quality of life, depression level and sleep quality of patients with combat-related extremity injury.

Full description

A total of 120 patients with combat-related extremity injury and 60 age and BMI-matched healthy controls will be participated in this cross-sectional study. The presence of neuropathic pain will be evaluated using Leeds assessment of neuropathic symptoms and signs (LANSS) questionnaire. The impact of pain on health-related quality of life will be assessed using the 36-Item Short Form Survey (SF-36). Beck Depression Scale (BDS) will be used to evaluate depression status of the patients. Quality of sleep will be assessed using the Pittsburgh Sleep Quality Index (PSQI).

Enrollment: 98 patients

Sex: Male

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients between the ages of 18-65 years who had previous history of combat-related extremity injury

Exclusion criteria

• Previous history of the cervical or lumbosacral radiculopathy, any known rheumatic disease or neurologic or endocrine disorders, excessive alcohol consumption and vitamin B12 deficiency

Trial design

98 participants in 2 patient groups

Case group 1

Description:

52 patients with score of 12 or more on Leeds assessment of neuropathic symptoms and signs (LANSS) questionnaire will be included in the neuropathic pain group.

Treatment:

Other: The effect of neuropathic pain on quality of life, depression and sleep quality

Case group 2

Description:

46 patients with scores less than 12 on LANSS will be included in the group without neuropathic pain.

Treatment:

Other: The effect of neuropathic pain on quality of life, depression and sleep quality