The Effect of neutrophil-to Lymphocyte Ratio in Preeclampsia- Eclampsia

Zekai Tahir Burak Women's Health Research and Education Hospital

Status: Unknown

Conditions: Preeclampsia; Eclampsia

Treatments: Other: normal neutrophil-to Lymphocyte ratio; Biological: high neutrophil to lymphocyte ratio

Study type: Observational

Funder types: Other

Identifiers

NCT01856387

Zekai Tahir Burak

Details and patient eligibility

About

Neutrophil/lymphocyte ratio (NLR) is a marker of systemic inflammation and endothelial dysfunction. In recent years, it has been reported that the individual components of the differential white cell count, specifically the neutrophil and lymphocyte counts,may have clinical utility in predicting diseases. An elevated NLR has been shown to be a prognostic indicator in various malignancies. İn the literature, many studies have been shown that NLR have predictive value in determining the prognosis of various diseases (cardiac or noncardiac diseases ). However, little is known about the predictive values of NLR in pregnancy complications. This study aimed to evaluate the potential predictive value of NLR in preeclampsia- eclampsia.

Full description

In recent years, have been reported that the individual components of the differential white cell count, specifically the neutrophil and lymphocyte counts, may have clinical utility in predicting diseases.

An elevated NLR has been shown to be a prognostic indicator in various malignancies. İn the literatüre have been shown that NLR have predictive value in determining the prognosis of various diseases (cardiac or noncardiac diseases.However, little is known about the predictive values of NLR and PLR in gestational DM, preeclampsia and the other pregnancy complications.

Retrospective data were collected for patients who was diagnosed with , preeclampsia- eclampsia, The NLR was defined as the absolute neutrophil count divided by the absolute lymphocyte count.

Enrollment: 600 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

pregnant women who developing preeclampsia eclampsia at pregnancy

Exclusion criteria

Known chronically maternal disease multiple pregnancy older than 40 years old

Trial design

600 participants in 2 patient groups

normal pregnancy outcomes

Description:

do not expect poor pregnancy outcomes on normal patients

Treatment:

Biological: high neutrophil to lymphocyte ratio

Other: normal neutrophil-to Lymphocyte ratio

adverse pregnancy outcome

Description:

high ratio of Neutrophil / lymphocyte ratio may predict preeclampsia eclampsia

Treatment:

Biological: high neutrophil to lymphocyte ratio

Other: normal neutrophil-to Lymphocyte ratio