The Effect of Nicardipine on Kidney Function During Orthognathic Surgery Under Hypotensive Anesthesia

Yonsei University

Status: Completed

Conditions: Healthy Subjects

Treatments: Drug: Nicardipine; Drug: remifentanil

Study type: Interventional

Funder types: Other

Identifiers

NCT01175746

3-2009-0196

Details and patient eligibility

About

Since nicardipine is known to protect kidney function, nicardipine infusion will result in better renal parameters measured in this study.

Enrollment: 46 patients

Sex: All

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy adult patients undergoing hypotensive anesthesia

Exclusion criteria

• patients with any co-morbidity

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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46 participants in 2 patient groups

nicardipine

Experimental group

Treatment:

Drug: Nicardipine

remifentanil

Active Comparator group

Treatment:

Drug: remifentanil