The Effect of Norepinephrine Versus Dopamine in Renal Transplant Recipients on Postoperative Graft Function

Assiut University

Status and phase: Unknown; Phase 3; Phase 2

Conditions: Renal Transplant

Treatments: Drug: Norepinephrine; Drug: Dopamine

Study type: Interventional

Funder types: Other

Identifiers

NCT03107858

NorepivsDopamine

Details and patient eligibility

About

Renal transplantation is now recognized as a treatment of choice for patients with chronic renal failure with end-stage renal disease. Renal transplantations are associated with better quality of life, better cost/benefit ratio, and possibly longer survival. Significant changes in blood pressure are common throughout the surgical procedure for kidney transplantation. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration.

Enrollment: 44 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled for a living donor kidney transplantation

Exclusion criteria

• Patients (less than 18 years old)
• Patients' refusal of consenting for enrolment in the study

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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44 participants in 2 patient groups

Norepinephrine

Active Comparator group

Treatment:

Drug: Norepinephrine

Dopamine

Active Comparator group

Treatment:

Drug: Dopamine