The Effect of Nutrition for the Colorectal Cancer Patients Receiving Chemotherapy-randomized Controlled Study

Chang Gung Medical Foundation

Status: Unknown

Conditions: Colorectal Cancer

Treatments: Dietary Supplement: Premium Amino Acids

Study type: Interventional

Funder types: Other

Identifiers

NCT04567459

202000035A3

Details and patient eligibility

About

We use clinical trial to explore the effect of nutrition support in colorectal cancer patients receiving postoperative adjuvant chemotherapy.

Full description

Colorectal cancer is the most common cancer in Taiwan. Side effects induced by postoperative adjuvant chemotherapy will affect nutrition status and may delay treatment and affect prognosis. Sarcopenia may be noted in some patients and increase the toxicities of chemotherapy. The studies of intervention include nutrition consultant and treatment like protein, fish oil or Vitamin D supplement. Premium amino acids include multiple amino acids and organic Selenium and have effect in inhibition of tumor proliferation according to colorectal cancer cell and animal experiments.

Enrollment: 100 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 20
• Radical operation for stage III and stage II with high risk colorectal cancer
• Agree to join the trial and sign the informed consent form

Exclusion criteria

• Unable to receive chemotherapy
• Unstable vital sign
• Not suitable after evaluation by Principal Investigator

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

100 participants in 2 patient groups

control group: chemotherapy

No Intervention group

Description:

No intervention

experimental group: chemotherapy and nutrition support

Experimental group

Description:

Premium amino acids 1pc bid for 6 months

Treatment:

Dietary Supplement: Premium Amino Acids