The Effect of Oily Fish and Poultry on Children's Cardiometabolic Health and Cognitive Function (FiSK Junior)

University of Copenhagen

Status

Completed

Conditions

Cognitive Function

Cardiometabolic Health

Treatments

Dietary Supplement: Oily fish

Dietary Supplement: Poultry

Study type

Interventional

Funder types

Other

Identifiers

NCT02809508

D218

H-16018225 (Other Identifier)

Details and patient eligibility

About

The purpose of FiSK Junior is to investigate whether intake of oily fish compared to poultry affects cardiovascular risk markers, cognitive function, and behaviour in healthy children.

Full description

The FiSK Junior study compares the effects of consuming oily fish versus poultry (control) in healthy 8-9 year-old Danish children. The children will be randomized to consume approximately 300 g/week of either oily fish or poultry for 12 weeks. Measurements and biological sampling will be performed at baseline and at the end of the intervention.

The main objective of the study is to investigate the effect on cardiovascular risk markers, primarily blood pressure and plasma triacylglycerol. Moreover, the effects on cognitive function, behaviour, emotions and physiological stress response will be assessed. In addition, change in n-3 long chain polyunsaturated fatty acid status (compliance), anthropometry, body composition, vitamin D status, inflammatory markers, growth markers, physical activity and diet will be measured. Outcomes will be analysed with focus on potential gender- and genotype-specific effects.

Enrollment

199 patients

Sex

All

Ages

8 to 9 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Children must:

Be 8 - 9 years of age at the start of the intervention
Be healthy
Like oily fish and chicken
Be willing to be randomized to eat fish or chicken
Not consume oily fish more than once per week 3 months prior to intervention start
Not consume fish oil 3 months prior to intervention start
Speak Danish in order to understand the study procedures

Moreover:

Parents must read and speak Danish, in order to be properly informed about the study procedures
The child must live in a household with ≤5 persons

Exclusion criteria

Serious chronic illnesses and diseases that may interfere with study outcomes
Diagnosed Attention Deficit Hyperactivity Disorder (ADHD) or other psychiatric illness
Intake of medication that may affect study outcomes
Concomitant participation in other studies involving dietary supplements or blood sampling
Living in a household with another participating child