The Effect of Oxytocin on Gastric Emptying

Skane University Hospital

Status: Completed

Conditions: Dyspepsia; Lack of Satiety

Treatments: Drug: oxytocin

Study type: Interventional

Funder types: Other

Identifiers

NCT01152047

2009/502 (Other Identifier)

Details and patient eligibility

About

The investigators have seen that oxytocin lowers satiety in healthy subjects. Patients with dyspepsia suffers from decreased accommodation and increased satiety postprandially. The investigators now want to examine whether oxytocin may diminish symptoms in these patients.

Full description

Patients will come twice for a slow satiety drinking test. Once they will get saline infusion and once oxytocin 40 mU/min. At the same time they register satiety on a VAS scale.

Enrollment: 14 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Dyspepsia

Exclusion criteria

• Age > 65 years
• Cardiac disease

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Double Blind

---

14 participants in 1 patient group

oxytocin, satiety

Experimental group

Description:

Oxytocin is given as infusion to examine if this decreases satiety compared to saline during a drinking test

Treatment:

Drug: oxytocin