The Effect of Oxytocin on the Gastric Emptying

Skane University Hospital

Status and phase: Completed; Early Phase 1

Conditions: Postprocedural Delayed Gastric Emptying

Treatments: Drug: oxytocin

Study type: Interventional

Funder types: Other

Identifiers

NCT00776360

29/2008

Details and patient eligibility

About

The investigators are going to examine whether oxytocin has a prokinetic effect on gastric emptying in patients suffering from gastro paresis. Oxytocin infusion will be compared with sodium chloride infusion.

Full description

The investigators are going to examine whether oxytocin has a prokinetic effect on gastric emptying in patients suffering from gastro paresis. Oxytocin infusion will be compared with sodium chloride infusion.The gastric emptying is estimade by sitntigraphy during 70 minutes, and performed twicw. Once with saline and once with oxytocin.

Enrollment: 12 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Gastroparesis in diabetics

Exclusion criteria

• Treatment with other prokinetics, other severe organic or psychological diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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12 participants in 2 patient groups, including a placebo group

oxytocin, gastric emptying

Experimental group

Description:

Oxytocin is given to study the gastric emptying rate

Treatment:

Drug: oxytocin

Drug: oxytocin

oxytocin

Placebo Comparator group

Description:

sodium chloride is given to study gastric emptying rate

Treatment:

Drug: oxytocin

Drug: oxytocin