The Effect of Periodontal Treatment on the Level of Free Radicals in the Saliva

B

Baruch Padeh Medical Center

Status

Unknown

Conditions

Periodontitis

Study type

Observational

Funder types

Other

Identifiers

NCT00969241
920090018-YR.ctil

Details and patient eligibility

About

This study will examine the relationship between free radicals in the saliva and periodontitis. 30 adults, 15 with periodontitis and 15 as a control group will give a sample of saliva before treatment and after treatment. The investigators will examine the free radicals in both groups.

Full description

Periodontal disease is a chronic adult condition. Bacteria implicated in the etiology of this disease causes destruction of connective tissue and bone. As a result of stimulation by bacterial antigen PMN produces free radicals via respiratory burst as a part of host response to infection. Free radicals can be defined as molecules or molecular fragments with an unpaired electron which imparts certain characteristics to the free radicals such as reactivity . Reactive free radicals are able to produce chemical modifications and to damage proteins, lipids, carbohydrates and nucleotides in the tissues.

Enrollment

30 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • older than 18
  • no medical problems

Exclusion criteria

medical problems

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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