The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section

Bakirkoy Dr. Sadi Konuk Training and Research Hospital

Status: Completed

Conditions: Analgesia; Anesthesia; Sexual

Treatments: Procedure: Patients undergoing transversalis fascia plane block; Procedure: Patients undergoing transversus abdominis plane block

Study type: Interventional

Funder types: Other

Identifiers

NCT05758233

2022-74

Details and patient eligibility

About

The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section under spinal anesthesia.

The main question[s] it aims to answer are:

[Is transversalis fascia plane block more effective in postoperative analgesia? ]

[Is there a difference between the duration of postoperative first analgesia requirement? ] Since the pain scores after the block at the end of the operation will be evaluated during the postoperative 24 hours, the participants will be asked to give a value between 0 and 10 in certain time periods.

Full description

This prospective, randomized trial was conducted at Başakşehir Çam and Sakura City Hospital by the Declaration of Helsinki. After ethics committee approval (decision no: 2022-74, date: 09.03.2022) and written informed consent was obtained from all patients, the trial was conduct-ed according to Consolidated Standards of Reporting Trials (CONSORT) guidelines.A total of 150 patients were divided into two groups: transversal fascia plane block (TFPB group) and Transversus abdominis plane block (TAPB group).VAS values, time to first analgesic requirement, analgesic requirements, nausea & vomiting and pruritus were evaluated for 24 hours postoperatively (6th hour (T2), 12th hour (T3), 24th hour .

Enrollment: 150 patients

Sex: Female

Ages: 20 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 20-50 years old pregnant woman
• ASAII-III
• Patients accepting spinal anesthesia

Exclusion criteria

• Morbid obesity(BMI >40)
• Patients who are switched to general anesthesia in an unexpected perioperative situation
• Patients with placental anomaly
• Patients with bupivacaine allergy
• Fetal distress situations too urgent to wait for spinal anesthesia and patients who do not want spinal anesthesia

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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150 participants in 2 patient groups

Grup 1: Transversalis Fascia Plane Block (TFPB)

Experimental group

Description:

Transversalis Fascia Plane Block (TFPB)

Treatment:

Procedure: Patients undergoing transversalis fascia plane block

Procedure: Patients undergoing transversus abdominis plane block

Grup 2: Transversus Abdominis Plane Block (TAPB)

Experimental group

Description:

Transversus Abdominis Plane Block (TAPB)

Treatment:

Procedure: Patients undergoing transversalis fascia plane block

Procedure: Patients undergoing transversus abdominis plane block