The Effect of Phosphatidylserine on Time Trial Performance in Trained Male Cyclists

Mark Glaister

Status: Unknown

Conditions: The Focus of the Study is to Investigate the Effects of Phosphatidylserine Supplementation on Exercise Physiology and Cycling Time-trial Performance

Treatments: Dietary Supplement: Phosphatidylserine

Study type: Interventional

Funder types: Other

Identifiers

NCT04967404

StMarysUC

Details and patient eligibility

About

Phosphatidylserine is a phospholipid found in high concentrations in the brain and nervous tissues along with naturally occurring in many foods. It has been extensively studied for its effects on improving cognitive function, learning, memory and alleviating stress. However, more recently it has been proposed that phosphatidylserine could improve exercise capacity. The mechanisms of proposed action are difficult to distinguish because of the limited research and therefore the purpose of this study is to identify the proposed mechanism of action of phosphatidylserine supplementation and to establish whether these mechanisms will have an effect on time trial performance in trained male cyclists.

Enrollment: 20 estimated patients

Sex: Male

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Cyclists
• Maximum oxygen uptake of at least 55 mL/kg/min

Exclusion Criteria:

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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20 participants in 2 patient groups, including a placebo group

Phosphatidylserine, 800 mg per day, 10 days

Experimental group

Treatment:

Dietary Supplement: Phosphatidylserine

Maltodextrin, 800 mg per day, 10 days

Placebo Comparator group

Treatment:

Dietary Supplement: Phosphatidylserine