The Effect of Phosphorus on Diet Induced Thermogenesis

Lebanese American University

Status: Completed

Conditions: Healthy; Imbalance of Constituents of Food Intake

Treatments: Dietary Supplement: Phosphorus; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT02594787

LAU.SOAS.MB1.2012.R1.11

Details and patient eligibility

About

The aim of the trial is to investigate the effect of ingestion of 75g of glucose (with or without phosphorus) on diet induced thermogenesis (using indirect calorimetry) and appetite (using visual analogue scales) in lean and obese healthy subjects

Enrollment: 23 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy
• Sedentary lifestyle
• Stable weight for the past 3 months
• On a balanced diet

Exclusion criteria

• Underweight (BMI<18.5) or overweight/obese (BMI≥25)
• age <18 or > 30 years
• Inability to give valid consent
• Presence of a chronic or acute illness.
• Elevated physical activity level (assesses by the physical activity questionnaire)
• Heavy smokers (≥1 pack per day).
• Weight gain or loss of > 3% in the past 3 months
• History of kidney stones

Trial design

23 participants in 2 patient groups, including a placebo group

Phosphorus

Active Comparator group

Description:

Intervention (500 mg of potassium phosphate) will be administered with 75 g glucose solution and diet induced thermogenesis will be measured afterwards

Treatment:

Dietary Supplement: Phosphorus

Placebo

Placebo Comparator group

Description:

Placebo (cellulose) will be administered with 75 g glucose solution and diet induced thermogenesis will be measured afterwards

Treatment:

Dietary Supplement: Placebo