The Effect of Photobiomodulation Using Low-Level Diode Laser Therapy on Postoperative Pain in Symptomatic Lower Molar Teeth With Irreversible Pulpitis and Apical Periodontitis; a Randomized Controlled Clinical Trial

Cairo University (CU)

Status: Not yet enrolling

Conditions: Effect of Photobiomodulation Using Diode Laser

Treatments: Other: Mock Laser Application; Device: Photobiomodulation by low level diode laser

Study type: Interventional

Funder types: Other

Identifiers

NCT06396130

ENDO 3-3-5 (29/4/24)

Details and patient eligibility

About

this study aims to assess the effect of photobiomodulation using low-level diode laser therapy on postoperative pain after single-visit root canal treatment of mandibular molars with symptomatic irreversible pulpitis and apical periodontitis.

Enrollment: 30 estimated patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• . Mature multirooted mandibular molar teeth with: i. Pre-operative sharp pain marked on the VAS scale by reading not less than 6. ii. Clinical diagnosis of symptomatic irreversible pulpitis with periapical periodontitis.

iii. Normal periapical radiographic appearance or slight widening in lamina dura. iv. Positive response and pain provoked by percussion.

• Patients who agree to provide written consent and attend for recall appointments.

Exclusion criteria

• Patients who used NSAIDs in the 24 hours before treatment.

• Medically compromised patients having significant systemic disorders. (ASA III or IV).

• Patients with two or more adjacent teeth requiring endodontic treatment.

• Pregnant or nursing females. 5. Teeth that have:

  i. Periodontal affection (with pocket depth greater than 5mm, associated with swelling orfistulous tract, or greater than grade I mobility).

ii. No possible restorability. iii. Signs of pulpal necrosis; associated sinus tract or swelling.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

30 participants in 2 patient groups, including a placebo group

Photobiomodulation using diode laser

Experimental group

Description:

Irradiation of periapical tissues with low level diode laser therapy buccally and lingually

Treatment:

Device: Photobiomodulation by low level diode laser

Placebo/ Mock Laser

Placebo Comparator group

Description:

Application of laser probe without device activation

Treatment:

Other: Mock Laser Application