The Effect of Plant Sterol Supplement on Blood Cholesterol

University of Oslo (UIO)

Status and phase: Completed; Phase 4

Conditions: High Blood Cholesterol Level

Treatments: Behavioral: Intake of plant sterols

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00485095

2.2006.3407

Details and patient eligibility

About

The purpose of this study is to determine whether supplement of plant sterol could lower blood cholesterol.

Enrollment: 41 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Men and women 18-80 years old
• Total cholesterol: 4.5-7.5 mmol/l
• Triglycerides at or below 4.0 mmol/l

Exclusion criteria

• BMI at or above 35 kg/m2
• Secondary hyperlipidemia, included diabetes
• Hypertension (at og higher than 170/110)
• Coronar, perifery or cerebral vascular disease last 3 months
• Familial hypercholesterolemia
• Change in dose of statins, oestrogen or contraceptives last 3 months
• Taking drugs which are known to interfere with the plasma level of cholesterol
• Chronic rheumatoid diseases or other diseases known to affect c-reactive protein
• Pregnancy
• Lactation
• Planning to reduce weight
• Taking plant sterols

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind