The Effect of Pre-operative Single Dose Antibiotic Prophylaxis on the Post-operative Implant Success

Biruni University

Status: Enrolling

Conditions: Tooth Loss

Treatments: Procedure: Dental implant placement; Drug: Antibiotic prophylaxis; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT04856319

Implant prophylaxis

Details and patient eligibility

About

There is no consensus on antibiotic prophylaxis in dental implant applications, and its necessity is controversial. Current reports on antibiotic use are insufficient. Also, other than antibiotic prophylaxis, data that may affect the post-operative situation such as the patient's gender, age, smoking, duration of surgery, length of the operation field, flap design have not been evaluated comprehensively.

This study aims to evaluate post-operative complications, implant success, and implant stability in 50 individuals: preoperative single dose of 2 g amoxicillin + clavulanic acid (25) and placebo (25).

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Tooth loss

Exclusion criteria

• Systemic disease
• Lactation/pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups, including a placebo group

Prophylaxis

Active Comparator group

Description:

2 g amoxicillin+clavulanic acid 1 hour prior to dental implant surgery

Treatment:

Drug: Antibiotic prophylaxis

Procedure: Dental implant placement

Placebo

Placebo Comparator group

Description:

placebo 1 hour prior to dental implant surgery

Treatment:

Procedure: Dental implant placement

Other: Placebo