The Effect of Prebiotics on Endurance Performance

Maastricht University

Status: Unknown

Conditions: Microtia

Treatments: Dietary Supplement: Prebiotic; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT04946578

Sport and microbiota

Details and patient eligibility

About

The aim of this study is to investigate the effect of a six-week period personalised food intervention with prebiotic supplementation on intense exercise performance in healthy, recreationally active adults.

Full description

The study conforms to a randomized, single-blinded, placebo-controlled parallel study design.

a prebiotic supplement will be selected based on a participants gut microbiota. 1 sachet of prebiotic or placebo will be given twice a day over a period of 6 weeks.

Before the start of the study, a VO2max test will be performed. Subjects will bring faecal samples which is collected at home. A time to exhaustion of approximately 80% of their VO2max will be performed at baseline and after the 6 weeks intervention period.

Enrollment: 34 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or female 18 - 40 y
• BMI range 18.5 - 25 kg/m2
• Recreational active (performing non-competitive physical endurance exercise at least two times per week with a minimum duration of 60 minutes per exercise bout)

Exclusion criteria

• Smoking
• Performing regular resistance training (3+ times per week, carrying out progressive overload training)
• Subject following an overly imbalanced or restrictive diet as per nutritional advice
• Participants who received antibiotics in the 90 days prior to the start of the study
• Self-admitted lactose intolerance
• Administration of probiotic or prebiotic supplements in the 14 days prior to the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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34 participants in 2 patient groups, including a placebo group

Prebiotic intervention group

Experimental group

Description:

Prebiotic supplementation

Treatment:

Dietary Supplement: Prebiotic

Placebo control group

Placebo Comparator group

Description:

Maltodextrin

Treatment:

Other: Placebo