The Effect of Pregabalin on the Spinal Anesthesia

K

Kyungpook National University

Status

Completed

Conditions

Block

Treatments

Drug: Placebo
Drug: Pregabalin

Study type

Interventional

Funder types

Other

Identifiers

NCT02690506
2014-05-027

Details and patient eligibility

About

Pregabalin, an anticonvulsant is widely used for treatment of neuropathic pain. Recently, it was reported that premedication of pregabalin before general anesthesia is effective to reduce postoperative pain. Up to date, there is no study about the effect of premedication of pregabalin on the spinal anesthesia. Therefore, in this study, investigators investigate the effect of premedication of pregabalin on the spinal anesthesia.

Full description

In this study, investigators investigate the effect of premedication of pregabaline 150 mg on the spinal anesthesia. Two hours before spinal anesthesia, placebo pill was administered to patients in the group C and pregabalin 150 mg was administered to patients in the group P, respectively. Time for the onset of blockade, cephalad level of analgesia and duration of analgesia were measured.

Enrollment

44 patients

Sex

All

Ages

19 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients of American Society of Anaesthesiologists Grades I and II

Exclusion criteria

  • Patients with infection at the puncture site, coagulopathy, having true hypersensitivity to drugs used, diabetes and hypertension, psychiatric and neurological diseases

Trial design

44 participants in 2 patient groups, including a placebo group

Group C
Placebo Comparator group
Description:
Oral placebo pill was administered 2 hours before anesthesia
Treatment:
Drug: Placebo
Group P
Active Comparator group
Description:
Oral pregabalin 150 mg was administered 2 hours before anesthesia
Treatment:
Drug: Pregabalin

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems