The Effect of Premedication on Postoperative Pain and Anxiety in Breast Cancer Surgery

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Status: Enrolling

Conditions: Female Patients Under the Age of 65 Who Will Undergo Breast Cancer Surgery

Treatments: Drug: Precedex and dormicum

Study type: Observational

Funder types: Other

Identifiers

NCT05647642

2022-09/2057

Details and patient eligibility

About

In this study, it was investigated whether the premedication drug administered before the surgery had an effect on postoperative pain and anxiety scores in female patients under the age of 65 who will undergo breast cancer surgery.

Full description

In this study, it was investigated whether the premedication drug administered before the surgery had an effect on postoperative pain and anxiety scores in female patients under the age of 65 who will undergo breast cancer surgery. The STAI-1(State Trait Anxiety İnventory ) form and APAIS (Amsterdam Preoperative Anxiety and İnformation Scale) scale were filled in for all preoperative patients. Afterwards, the patients were treated with either midazolam or dexmedetothymidine, depending on the anesthesiologist's preference. After administration, he was taken to surgery. As intraoperative analgesics, 2 mg/kg tramadol and 15 mg/kg paracetamol were administered to all patients. postoperative recovery time (aldrete 10), 1., 2.,6.,12.,24. VAS score, postoperative nausea-vomiting scale, STAI-1(State Trait Anxiety İnventory ) form, first need time if postoperative analgesic was needed, and 24-hour total analgesic consumption were recorded. It was aimed to examine the effects of different premedications on postoperative pain and anxiety

Enrollment: 80 estimated patients

Sex: Female

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ASA 1-2-3
• 18-65 aged
• Female patients

Exclusion criteria

• Under 18 years old and over 65 years old
• Having a history of cerebrovascular disease illiteracy
• Have visual and auditory problems İnability to cooperate with cognitive function test
• Having emergency surgery
• Those who are unable to read, understand and sign the consent form
• Patients deemed unsuitable by the investigator

Trial design

80 participants in 4 patient groups

low dose midazolam

Description:

0,025 mg/kg Midazolam

Treatment:

Drug: Precedex and dormicum

high dose midazolam

Description:

0,05 mg/kg Midazolam

Treatment:

Drug: Precedex and dormicum

low dose dexmedetothymidine

Description:

0.5 mg/kg dexmedetothymidine 10 minute infusion

Treatment:

Drug: Precedex and dormicum

high dose dexmedetothymidine

Description:

1mg/kg dexmedetothymidine 10 minute infusion

Treatment:

Drug: Precedex and dormicum