The Effect of Preoperative Gabapentin on Postoperative Pain Control and Analgesic Requirements Following Bariatric Surgery

Ain Shams University

Status: Not yet enrolling

Conditions: Bariatric Surgery Analgesia

Treatments: Drug: Group 2; Drug: Group 1

Study type: Interventional

Funder types: Other

Identifiers

NCT07169006

MD326/2024

Details and patient eligibility

About

The importance of bariatric anesthesia and analgesia research cannot be ignored as it can inform and improve the perioperative protocols for other patients with morbid obesity irrespective of the surgical procedures they are undergoing

Full description

Among various postoperative complications, pain is the main adverse event experienced by patients. Good control of postoperative pain is an important factor for reducing early postoperative complications such as pulmonary embolism, deep vein thrombosis, ileus, and respiratory infections, and for decreasing length of stay, lowering costs, and increasing patient satisfaction

Enrollment: 102 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with American Society of Anesthesiologists physical status ASA I to III
• both genders
• Morbid obese scheduled for bariatric surgery

Exclusion criteria

• patients with impaired liver or kidney disease
• patients with history of hypersensitivity to gabapentin
• patients with history of alcohol abuse, chronic pain or frequent use of analgesic
• patients with uncontrolled medical disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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102 participants in 2 patient groups, including a placebo group

Group 1

Experimental group

Description:

Will receive a single dose of gabapentin 300 mg preoperatively before standard general anesthesia

Treatment:

Drug: Group 1

Group 2

Placebo Comparator group

Description:

will receive a placebo before standard general anesthesia

Treatment:

Drug: Group 2