The Effect of Preoperative Intravenous Fluid Bolus on Post-induction Hypotension in Elective Cystoscopies.

University of Missouri (MU)

Status and phase: Invitation-only; Phase 4

Conditions: Hypotension During Surgery; Postinduction Hypotension

Treatments: Drug: Lactated Ringers

Study type: Interventional

Funder types: Other

Identifiers

NCT06985654

2126906

Details and patient eligibility

About

This study aims to determine whether a standardized, weight-based crystalloid fluid bolus administered preoperatively reduces the incidence of postinduction hypotension (PIH) in patients undergoing cystoscopy.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age ≥ 18 years old.
2. Undergoing elective cystoscopy surgery as the primary procedure.
3. Able to provide informed consent.

Exclusion criteria

1. Emergency surgeries.
2. Past history of amputations of any body part.
3. Allergies or contraindications to any medications used in the protocol or lactated ringers.
4. Systolic heart failure with LVEF < 30% within the last year.
5. Severely depressed RV function within the last year.
6. Restrictive diastolic dysfunction within the last year.
7. Currently pregnant.

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

No Treatment

No Intervention group

Description:

Patients will receive an ultrasound scan on their heart to determine cardiac output before surgery, but no fluid bolus will be given.

Preoperative Fluid Bolus

Experimental group

Description:

Patients will receive an ultrasound scan on their heart to determine cardiac output and will also receive a fluid bolus of Lactated Ringers before surgery.

Treatment:

Drug: Lactated Ringers