The Effect of Prophylactic Hemodialysis on the Morbidity and Mortality of the Patients With Chronic Kidney Disease Stages 3-4 Undergoing Coronary Artery Graft Bypass

Imam Khomeini Hospital

Status and phase: Unknown; Phase 3; Phase 2

Conditions: Coronary Artery Disease; Chronic Kidney Disease stage3; Chronic Kidney Disease stage4

Treatments: Procedure: hemodialysis

Study type: Interventional

Funder types: Other

Identifiers

NCT01410617

THC-473

Details and patient eligibility

About

Coronary artery disease is a major cause of death in patients with renal dysfunction Among patients who undergo coronary artery bypass grafting ,renal dysfunction is known To be a major predictor of in-hospital and remote mortality As little is known about the impact of non-dialysis-dependent renal dysfunction on short and mid term Outcomes following coronary surgery we have decided to investigate the effect of prophylactic Hemodialysis on the mortality and morbidity of the patients with ckd (stage 3,4 ) and compare these Effect with the control group

Enrollment: 120 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 80<age>18
• ckd patients with stage 3,4
• CABG for the first time

Exclusion criteria

• age<18
• previous CABG (coronary artery bypass grafting)
• AKI(acute kidney injury)
• dialysis patients

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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120 participants in 2 patient groups

dialysis

Active Comparator group

Description:

the patients who undergo 3 sessions prophylactic hemodialysis

Treatment:

Procedure: hemodialysis

control group

No Intervention group

Description:

the patients who do not undergo hemodialysis