The Effect of Protein Ingestion on the Recovery of Skeletal Muscle Function Following Eccentric Exercise. (SPADE)

University of Exeter

Status: Completed

Conditions: Healthy

Treatments: Dietary Supplement: Post exercise protein-polyphenol supplement; Dietary Supplement: Pre bed protein-polyphenol supplement; Dietary Supplement: Post exercise placebo supplement; Dietary Supplement: Pre bed placebo supplement

Study type: Interventional

Funder types: Other

Identifiers

NCT02980900

181739

Details and patient eligibility

About

The present study will assess the effect of the type and timing of protein ingestion 6 days prior to, and 7 days following eccentric exercise on the time course of 1) the recovery of muscle function, 2) the recovery of perceived muscle soreness, 3) muscle metabolism.

Enrollment: 36 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Men and women who are generally healthy and recreationally active

Exclusion criteria

• Active cardiovascular disease or hypertension
• Diagnosed metabolic impairment
• Use of nutritional supplements
• Use of anti-inflammatory medications
• Habitual dietary protein intake of <0.8g/kg/day
• Musculoskeletal disorders

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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36 participants in 4 patient groups, including a placebo group

Placebo supplement

Placebo Comparator group

Description:

Post exercise placebo supplement Pre bed placebo supplement

Treatment:

Dietary Supplement: Pre bed placebo supplement

Dietary Supplement: Post exercise placebo supplement

Post exercise supplement

Active Comparator group

Description:

Post exercise protein-polyphenol supplement Pre bed placebo supplement

Treatment:

Dietary Supplement: Post exercise protein-polyphenol supplement

Dietary Supplement: Pre bed placebo supplement

Pre bed supplement

Active Comparator group

Description:

Post exercise placebo supplement Pre bed protein-polyphenol supplement

Treatment:

Dietary Supplement: Pre bed protein-polyphenol supplement

Dietary Supplement: Post exercise placebo supplement

Post exercise + pre bed supplement

Active Comparator group

Description:

Post exercise protein-polyphenol supplement Pre bed protein-polyphenol supplement

Treatment:

Dietary Supplement: Post exercise protein-polyphenol supplement

Dietary Supplement: Pre bed protein-polyphenol supplement