The Effect of Quadratus Lumborum (QL) Block on the Incidence of Chronic Neuropathic Pain After Retroperitoneal Laparoscopic Donor Nephrectomy: A Study on Neuroinflammation and Neurophysiology

University of Indonesia (UI)

Status: Not yet enrolling

Conditions: Laparoscopic Donor Nephrectomy; Quadratus Lumborum Block; Chronic Pain; Living Kidney Donor

Treatments: Drug: Injection of normal saline; Drug: injection of local anesthesia solution

Study type: Interventional

Funder types: Other

Identifiers

NCT07037992

QLChronicNeuropathicPostOpPain

Details and patient eligibility

About

To analyze the relationship of anterior subcostal quadratus lumborum (QL) block compared with control block on the incidence of chronic neuropathic pain at three months post-laparoscopic retroperitoneal living kidney donor.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Living kidney donor candidate patients aged 18-65 years Patients with ASA physical status assessment 1-3 Patients are willing to be research subjects.

Exclusion criteria

• The patient was known to have a history of chronic non-cancer pain and cancer pain.

The patient had a history of preoperative laparoscopic kidney donor surgery.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

Quadratus Lumborum Block

Experimental group

Treatment:

Drug: injection of local anesthesia solution

Quadratus Lumborum Sham Block

Placebo Comparator group

Treatment:

Drug: Injection of normal saline