The Effect of Remifentanil Infusion During Emergence on the Incidence of Emergence Delirium

Yeungnam University College of Medicine

Status: Unknown

Conditions: Delirium

Treatments: Drug: Placebo; Drug: Remifentanil

Study type: Interventional

Funder types: Other

Identifiers

NCT02108795

apsj20140331

Details and patient eligibility

About

The aim of the present study is to assess the effect of postoperative remifentanil infusion on the incidence of emergence agitation in preschool-aged children undergoing strabismus surgery with sevoflurane anaesthesia.

Full description

Patients are randomly assigned to one of two groups. Anesthesia is maintained with sevoflurane and remifentanil infusion. All patients received a predetermined concentrations of remifentanil according to their group assignments (control group, remifentanil 0 ug/kg/min; remifentanil group, remifentanil 0.05 ug/kg/min) from 10 minutes before the end of surgery to discharge from postanesthetic care unit. emergence agitation is assessed during the emergence phase.

Enrollment: 86 estimated patients

Sex: All

Ages: 3 to 7 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists physical status I and II
• preschool-aged children undergoing strabismus surgery

Exclusion criteria

• psychological disorders
• emotional disorders
• abnormal cognitive development
• developmental delay
• allergy to the drugs in our protocol

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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86 participants in 2 patient groups, including a placebo group

remifentanil group

Experimental group

Description:

Remifentanil 0.05 ug/kg/min is infused to the patients.

Treatment:

Drug: Remifentanil

control

Placebo Comparator group

Description:

Normal saline 0.2 ml/kg/hour is infused to the patients

Treatment:

Drug: Placebo