The Effect of Resistance Exercise on Inflammation in Young and Older Adults

National Taiwan Normal University

Status: Completed

Conditions: Aging; Inflammatory Response

Treatments: Other: Resistance exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT05042167

202012HM020

Details and patient eligibility

About

Healthy young and older adults will complete two trials in a randomized crossover counter-balanced order, including resistance exercise and sedentary control. During each trial, blood samples will be collected.

The investigators hypothesized that an acute bout of resistance exercise exert different inflammation responses in young and older adults.

Enrollment: 16 patients

Sex: Male

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age: 20-80
• Healthy male
• Without experience of resistance training

Exclusion criteria

• No acute or chronic musculoskeletal symptoms
• Smoking
• Alcohol or drug abuse
• Fail to conduct resistance exercise

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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16 participants in 2 patient groups

High-load resistance exercise

Experimental group

Description:

Subjects in high-load trial performed 3 sets per exercise, 8 repetitions with load of 70%-1RM with 90 sec of rest between sets, followed by a fourth set to voluntary failure.

Treatment:

Other: Resistance exercise

Sedentary control

No Intervention group

Description:

Subjects in control trial stayed sedentary during the period.